Decode Age
Decode Age Store
  • Decode Age Support
    • Shipping
      • Cash on Delivery: How Does It Work at Decode Age?
      • Is Free Shipping Really Free in Decode Age?
      • How can I track my order?
      • Changing Your Order's Shipping Address at Decode Age
      • How Do I Get My Money Back for Returns at Decode Age?
      • Are Decode Age's Packing Materials Environmentally Friendly?
      • What If My Decode Age Package is Missing?
      • Can I Ship My Decode Age Order to an Address Different from My Profile?
      • Are There Shipping Fees for My Decode Age Order?
      • Does Decode Age Ship Orders Internationally?
      • When Can I Expect My Decode Age Order to Arrive?
      • Minimum Purchase Requirements at Decode Age
    • Refund
      • Payment methods
      • Not Sure About Your Purchase? Our 30-Day Return Guide
      • What if I'm unsatisfied with an opened product?
    • Return and Exchange
      • Received Something Different? Here's How to Exchange It
      • How Do I Exchange My Decode Age Product?
      • Is it possible to return internationally shipped products?
    • Pricing
      • Pricing and Taxes on Your Decode Age Orders
      • Why Are High-Quality Supplements from Decode Age More Expensive?
    • Quality & Certification
      • What is the significance of FDA registration for Decode Age?
      • Why are all Decode Age supplements Pharmaceutical Grade?
      • What is the difference between Pharmaceutical and Nutraceutical Grade supplements?
      • What is the Purity and Efficacy of Decode Age Supplement?
      • What Certifications Do Your Decode Age Supplements Have?
    • Know about Side Effects
      • Are there any side effects to using Decode Age supplements?
    • Customer Support
      • Contact: How can I contact Customer Support for my queries?
    • Health Condition
      • What Supplements Help with Arthritis?
      • The Potential of Decode Age Supplements for Managing Diabetes
      • Which Supplements Help with Menopausal Symptoms?
    • Decode Biome (Gut Microbiome Test)
      • What is Decode Biome Test?
      • How to use Decode Biome Test
      • Who Can Benefit from a Gut Microbiome Test?
      • Why Should I Get a Decode Biome Test?
      • What is Biome Questionnaire?
      • How is the Decode Biome Test Better?
      • Report Insights
    • Decode Blood Age
      • What is BloodAge Test ?
      • Why Should I Get a Decode BloodAge Test?
      • Biological Age Vs Chronological Age
      • Report Insights
      • Comprehensive Blood Report
      • Personalized Action Plan
    • Supplement Information
      • NMN Supplement
        • What are the benefits of NMN Supplement?
        • What is NMN (Nicotinamide Mononucleotide) and how does it work?
        • Why and How to Choose the Right NMN Supplement
        • Can I Take NMN? Understanding Dosage and Guidelines
        • Why Choose Uthever® NMN Over Regular NMN?
        • NMN Powder vs NMN Capsules: Which Is Best for Longevity?
        • NMN Powder Detailed Benefits
        • Is Beta or 'β' NMN the same as NMN?
        • Benefits and Convenience with NMN Capsules
        • Taking NMN While Fasting: Does It Work? A Guide to Benefits & Usage
        • Difference Between NMN and LongeVit. Do I need to take both?
        • Does NMN Increase Testosterone Levels?
        • Why is liposomal NMN form better than regular NMN?
      • LongeVit Supplement
        • How is LongeVit Best selection for NMN User?
        • Can I consume LongeVit? Understanding Dosages and Guidelines
      • Trans Resveratrol Supplement
        • Japanese Knotweed: Benefits and Uses Explained
        • Difference Between Trans-Resveratrol and ResVit
        • Can I Take Trans Resveratrol? Understanding Dosage and Guidelines
        • What is Trans- Resveratrol? And how does it work?
        • What are the Benefits of Trans-Resveratrol Supplement?
      • Ca-AKG Supplement
        • Difference between AKG, Ca-AKG, and AAKG and Why Ca-AKG Stands Out?
        • What is Ca-AKG (Calcium Alpha-Ketoglutarate) and how does it work?
        • Can I take Ca-AKG? Understanding Dosages and Guidelines
        • How does Ca-AKG supplementation reduce biological age?
      • Spermidine Supplement
        • What is Spermidine? How does it work?
        • Can I take Spermidine? Understanding Dosage and Guidelines
        • What is Autophagy?
      • TMG Supplement
        • What are the benefits of taking TMG supplements?
        • Can I consume TMG? Understanding Dosages and Guidelines
      • Trans Pterostilbene Supplement
        • What is Trans Pterostilbene? How does it work?
        • Can I take Trans-Pterostilbene? Understanding Dosage and Guidelines
      • Quercetin Supplement
        • What is Quercetin? How Does it work?
        • Can I take Quercetin? Understanding Dosages and Guidelines
        • What are the benefits of Quercetin?
      • Fisetin Supplement
        • What is Fisetin? How does it work?
        • Can I Take Fisetin? Understanding Dosage and Guidelines
      • SeneVit Supplement
        • What is SeneVit? How does it work?
        • Can I Take SeneVit? Understanding Dosage and Guidelines
        • Should I take SeneVit instead of Fisetin and Quercetin?
      • SportVit Supplement
        • What is SportVit? Why is the best Pre-workout?
        • Can I Take SportVit? Understanding Dosage and Guidelines
      • ResVit Supplement
        • What is ResVit?
        • Can I take ResVit? Understanding Dosages and Guidelines
        • Should I Take ResVit Instead of Trans-Resveratrol and Trans-Pterostilbene?
      • Mag7- Seven Magnesium Complex
        • What is Mag7™ ? How does it work?
        • Can I take Mag7™ ? Understanding Dosage and Guidelines
        • How does Mag7™ help with sleep?
        • Mag7™ Capsules vs Mag7™ Powder
      • CoQ10
        • What is CoQ10 (Coenzyme Q10)? How does it work?
        • Can I take CoQ10 (Coenzyme Q10)? Understanding Dosage and Guidelines
        • Why is Piper nigrum extract (black pepper) an important ingredient in our supplement?
      • Nicotinamide Riboside (NR)
        • What is NR (β-NR 300 /Beta Nicotinamide Riboside)? How Does It Work?
        • Can I Take NR? Understanding Dosage and Guidelines
      • DAKE
        • What is DAKE®?
        • Can I take DAKE®? Understanding Dosage and Guidelines
      • OptiAge Collagen
        • What is OptiAge™ Collagen? How does it work?
        • Can I take OptiAge™ Collagen Powder? Understanding Dosage and Guidelines
        • What is HydroPeach?
    • Frequently Asked Questions
      • Decode Age on Shark Tank
      • What Supplement should I start with?
      • Decode Age Portfolio
      • Decode Age External Links
      • Storing Decode Age Supplements: Tips and Recommendations
      • Space Travel and Its Impact on Astronauts' Bone Health
      • Decoding Sirtuins and NAD connection
      • What if I have a reaction to one of your products?
      • Who can take these supplements?
      • What Is Shelf Life for Decode Age Products?
      • Decode Age is Now DA1: A New Chapter in Longevity and Wellness
Powered by GitBook
On this page
  • Understanding Biological Ageing
  • Ca-AKG and its Effects on Biological Age
  • Conclusion
  • Reference

Was this helpful?

  1. Decode Age Support
  2. Supplement Information
  3. Ca-AKG Supplement

How does Ca-AKG supplementation reduce biological age?

This article talks about biological age and how Ca-AKG supplementation reduces it.

Last updated 5 months ago

Was this helpful?

Understanding Biological Ageing

To understand how Ca-AKG reduces biological age, it's essential to grasp the concept of biological ageing itself. Unlike chronological age, which simply reflects the passage of time, biological age reflects the functional state of an organism's cells and tissues. Biological ageing is influenced by various factors, including oxidative stress, DNA damage, and cellular dysfunction, all of which contribute to the gradual decline in physiological function over time.

Ca-AKG and its Effects on Biological Age

The study investigated the potential of Rejuvant, a natural mocktail comprising Ca-AKG (Calcium alpha-ketoglutarate) and specific vitamins tailored to each sex, in mitigating biological ageing in humans. Employing DNA methylation (DNAm) clocks as a reliable ageing biomarker, the study aimed to assess the impact of Rejuvant supplementation on biological age reversal.

In the design, 42 individuals were recruited, and they consumed Rejuvant, containing AKG and vitamins, for an average duration of 7 months. DNAm analysis was conducted at baseline and post-rejuvenate supplementation to monitor changes in biological age.

The results were compelling, revealing an average reduction in biological ageing by 8 years among the individuals. This reduction signifies a significant reversal or delay in the ageing process, indicating the potential efficacy of Rejuvant in promoting youthfulness and vitality.

Furthermore, this study observed that Rejuvant exhibited greater benefits among individuals who were both chronologically and biologically older. This finding suggests that Ca-AKG supplementation may be particularly advantageous for individuals facing advanced stages of ageing

Conclusion

In conclusion, Ca-AKG represents a groundbreaking advance in the field of anti-ageing research, offering a promising strategy for reducing biological age and promoting healthy ageing. By targeting key molecular pathways implicated in ageing processes, Ca-AKG holds the potential to extend lifespan, improve health span, and enhance the quality of life for individuals worldwide.

Reference

Demidenko, O., Barardo, D., Budovskii, V., Finnemore, R., Palmer III, F. R., Kennedy, B. K., & Budovskaya, Y. V. (2021). Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test. Aging (albany NY), 13(22), 24485.

Decode Age products are not intended to diagnose, treat, or cure diseases.

study
(Demidenko et al., 2021).
https://doi.org/10.18632/aging.203736