> For the complete documentation index, see [llms.txt](https://help.decodeage.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://help.decodeage.com/decode-age-support/product-guides/spermidine.md).

# Spermidine

* **What it is:** spermidine trihydrochloride, a compound studied for its role in autophagy, the body's cellular recycling.
* **What is inside (per capsule):** spermidine trihydrochloride 10 mg. 60 vegetarian capsules a bottle.
* **How to take it:** 1 capsule after dinner. You can go up to 2 a day (1 after lunch, 1 after dinner) if your doctor advises. A bottle lasts 60 days at 1 a day.
* **Check first:** avoid during pregnancy or breastfeeding. Please consult your doctor if you have a bleeding disorder or take blood thinners. Not for children.
* **Buy it:** [Spermidine](https://decodeage.com/products/spermidine?utm_source=help_centre)

Our products are not intended to diagnose, treat, cure or prevent any disease.

## Common questions

### What is spermidine trihydrochloride?

Spermidine is a natural compound involved in autophagy, the body's cellular self-cleaning process. Spermidine trihydrochloride is a stable, bioavailable form of it.

### How many capsules are in a bottle of Spermidine?

Each bottle contains 60 vegetarian capsules of 10 mg, which lasts 60 days at 1 capsule a day, or 30 days at 2 capsules a day.

### How do I take Spermidine?

Take one capsule after dinner. You may go up to two capsules (one after lunch, one after dinner) if your healthcare practitioner advises. A 60-capsule bottle lasts 60 days at one a day, or 30 days at two. The capsules are vegetarian.

### Can I take Spermidine while pregnant or breastfeeding?

It should be avoided. Research on spermidine during pregnancy and breastfeeding is limited, so supplementation is advised against during these periods.

### Can I take Spermidine if I take blood thinners or have a bleeding disorder?

Consult your physician first. Medical advice is recommended before taking Spermidine if you have a bleeding disorder or take blood-thinning medication.

### What is the difference between wheat germ spermidine and spermidine trihydrochloride?

Wheat germ extract is a natural food source of spermidine, while spermidine trihydrochloride is a synthetic, water-soluble form. Our Spermidine uses spermidine trihydrochloride, at 10 mg per capsule.

### What should I look for in a spermidine supplement?

Check for high purity and a clearly stated mg of spermidine per serving, gluten-free status if you are sensitive, and third-party testing. We offer Spermidine Trihydrochloride with 10 mg per vegetarian capsule, taken 1 capsule after dinner.

### How much spermidine per day?

There is no single ideal dose; research and expert recommendations point to 1 to 10 mg daily. Our Spermidine provides 10 mg per capsule: 1 capsule after dinner, which the label says may be increased to 2 capsules, one after lunch and one after dinner, or as advised.

### When is the best time to take spermidine?

Evening is commonly suggested, with or shortly after a light dinner, because autophagy is linked to the body's overnight repair cycle. Our Spermidine is labelled 1 capsule after dinner.

### What are the benefits of spermidine?

Spermidine is a naturally occurring polyamine studied for its role in autophagy, the body's process of breaking down and recycling damaged cellular components, which supports cellular renewal. Our Spermidine provides 10 mg spermidine trihydrochloride per capsule; take 1 capsule after dinner.

### Can spermidine reverse grey hair?

There is not enough evidence to say so. Our Spermidine is formulated to support autophagy, not to change hair colour.

**Next step:** [Buy Spermidine](https://decodeage.com/products/spermidine?utm_source=help_centre\&utm_medium=gitbook\&utm_campaign=spermidine), or read [Cellular Health, Autophagy and Mitochondria](/decode-age-support/learn/cellular-health-autophagy-and-mitochondria.md).