What is CoQ10 (Coenzyme Q10)? How does it work?
Get an in-depth understanding of CoQ10 (Coenzyme Q10) and how it works.
What is CoQ10 (Coenzyme Q10)?
Coenzyme Q10 (CoQ10), also known as ubiquinol, is a fat-soluble, vitamin-like molecule naturally present in every cellular membrane within our bodies. It plays a crucial role in cellular energy production. Acting as a potent antioxidant, CoQ10 helps protect cells from oxidative damage and supports overall metabolic function.
Discovery and Background
It was first identified in 1940, and isolated from the mitochondria of the beef heart, in 1957. Coenzyme Q10 is also known as Coenzyme Q, CoQ10, Ubiquinone or Vitamin Q10.
CoQ10 is a nutrient that plays a vital role in energy production within cells and acts as a powerful antioxidant. It exists in two forms: ubiquinone and ubiquinol.
Ubiquinone is the oxidized form of CoQ10. It must be converted into ubiquinol, the reduced and active antioxidant form, to be effectively utilized by the body. Ubiquinol is more bioavailable, allowing for better absorption.
What are the Sources of Coenzyme Q10(CoQ10)?
Meat, fish, nuts, and some oils are the richest nutritional sources of CoQ10, while much lower levels can be found in most dairy products, vegetables, fruits, and cereals.
While most individuals typically obtain adequate levels of CoQ10 through a balanced diet, supplementation can be beneficial in certain cases.
What are the Benefits of CoQ10?
Powerful Antioxidant: Protects your cells from oxidative stress and damage caused by free radicals. *
Enhances Heart Health: Contributes to healthy heart function and helps maintain normal blood pressure. *
Supports Cellular Energy Production: Helps your cells generate energy, which is crucial for overall vitality and stamina. *
Mitochondrial Health: Enhances mitochondrial health by facilitating energy production and supporting overall cellular function and vitality. *
Metabolic Health: Supports healthy metabolism, cellular energy production, antioxidant protection and maintains energy levels throughout the day. *
Enhances Muscle Health: Reduces muscle fatigue and inflammation, improves exercise performance, enhances muscle endurance and efficiency. *
What are the Side Effects of CoQ10?
No serious side effects of CoQ10 have been reported. Mild side effects such as insomnia or digestive upsets may occur. CoQ10 is safe as a dietary supplement.
Daily intakes of up to 1200 mg/d are generally well tolerated, with typical dosages ranging from 100 to 200 mg/d.
CoQ10 may interact with the anticoagulant (blood thinner) warfarin and the diabetes drug insulin.
Individual responses to supplements can vary and it’s best to consult with a healthcare provider for personalized advice.
REFERENCES
Sood B, Patel P, Keenaghan M. Coenzyme Q10. [Updated 2024 Jan 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK531491/
Saini, R. (2011). Coenzyme Q10: The essential nutrient. Journal of Pharmacy and Bioallied Sciences, 3(3), 466. https://doi.org/10.4103/0975-7406.84471
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