Does NMN Increase Testosterone Levels?

The potential of nicotinamide mononucleotide (NMN) in boosting testosterone levels, particularly in ageing men, has garnered significant interest. Here's an in-depth look at how NMN may influence testosterone production and its health implications:

NAD+ and Testosterone

Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in every cell of the body that plays a crucial role in various biological processes. One of its important functions is in the synthesis of testosterone, the primary male sex hormone responsible for muscle development, bone density, and overall health. NAD+ supports this process by enhancing the activity of 3β-Hydroxysteroid Dehydrogenase, an essential enzyme required for the biosynthesis of steroid hormones, including testosterone.

The Role of NMN in Boosting Testosterone

NMN, a synthesized form of vitamin B3, has gained attention for its ability to boost NAD+ levels in cells. As discussed previously, NAD+ is essential for testosterone synthesis. Therefore, increased levels of NAD+ can potentially lead to elevated testosterone production. In addition, NMN may also directly stimulate enzymes involved in steroidogenesis, the process of producing steroid hormones, including testosterone.

Scientific Studies Linking NMN and Increased Testosterone

The potential of NMN in boosting testosterone levels has been supported by scientific studies. In one study, conducted by Yamauchi and colleagues from the University of Tokyo, it was found that NMN supplementation can significantly influence testosterone levels in ageing men. This study was groundbreaking as it provided concrete evidence of NMN's impact on testosterone levels in humans, previously observed in rodent studies. The results also showed an improvement in muscle strength and performance in the men who underwent NMN supplementation, which further supports the potential of NMN in promoting male health.

Future Research and Considerations

While the initial findings are promising, there is a need for further research to fully understand the potential of NMN in boosting testosterone levels. This study involved a small group of healthy men, and therefore, it would be beneficial to replicate the study on a larger and more diverse population, including women. Additionally, further investigation is required to determine the specific mechanisms through which NMN influences testosterone production.

FAQs in Relation to Does NMN Increase Testosterone Levels?

What is NMN and what can it do for men?

Nicotinamide Mononucleotide (NMN) is a molecule that may help increase energy levels, improve cognitive function, and potentially boost testosterone production in men.

According to research, NMN may have anti-ageing properties and could potentially improve overall health.

Can NAD+ affect testosterone levels?

While there is no direct link between NAD+ and testosterone, increasing NAD+ levels might indirectly influence testosterone by improving overall cellular health and metabolic functions, according to studies.


In conclusion, the study by Yamauchi and colleagues highlights the potential of NMN to boost testosterone levels in ageing men. This presents an exciting possibility for addressing age-related health concerns related to testosterone and muscle function. While more research is needed, these initial findings indicate that NMN may be a valuable tool for enhancing testosterone levels and promoting overall male health in the context of ageing. Consult with a healthcare professional to determine if NMN supplementation is a suitable option for you.

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