What is Trans Pterostilbene? How does it work?

Get an in-depth understanding of Trans Pterostilbene and how it works.

What is Trans-Pterostilbene?

Pterostilbene is a naturally occurring compound found in various plants, most notably in blueberries. It belongs to the stilbene group, similar to resveratrol, but with some differences that may make it more beneficial for health. Pterostilbene is known for its antioxidant properties, which can protect the body against damage from free radicals.

Discovery and Background

First identified in 1977 by Langcake and Pryce, pterostilbene has been the subject of research due to its potent antioxidant capabilities.

Sources of Pterostilbene

Pterostilbene is primarily found in blueberries, but the amount present in these fruits is relatively small. To achieve the levels used in some studies, one would have to consume an impractically large quantity of blueberries. Thus, supplements are a more feasible source for those looking to incorporate higher doses of pterostilbene into their diet. Other sources include almonds, grape leaves, cranberries, and several other Vaccinium berries.

Which is better, resveratrol or pterostilbene?

Comparing pterostilbene to resveratrol, pterostilbene is more bioavailable due to its chemical structure. This means it's absorbed and utilized by the body more efficiently than resveratrol. Although resveratrol has been more extensively studied, pterostilbene is emerging as a potentially more effective option due to its higher bioavailability and similar health benefits.

Health Benefits of Trans Pterostilbene

Pterostilbene has been associated with a range of health benefits. It exhibits anti-inflammatory, anticarcinogenic, and antioxidant properties. Research suggests it may protect against cardiovascular diseases, improve cognitive function, and support cellular energy metabolism by activating pathways associated with longevity. Its potential in treating neurodegenerative diseases and conditions like arthritis has also been explored.

Side Effects and Safety

At doses up to 250 mg per day, pterostilbene has been considered safe without significant adverse effects reported. However, some people may experience increased LDL cholesterol when using it. Given this compound is commonly found in food, dietary levels of pterostilbene should be safe.


While promising, the research on pterostilbene is still in the early stages compared to resveratrol. Its increased bioavailability and potential health benefits make it an intriguing subject for further study. As with any supplement, it's important to consult with a healthcare professional before starting use, especially at the higher doses available through supplements.

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